Indian Hill's Ben Bayless went 16:17.72 to claim the Division II victory at the Troy Region meet.
West Liberty-Salem's Megan Adams secured the Division III win with her 18:51.48 clocking.
Middletown stand-out, Conant Smith claimed his sixth victory of the season at the OHSAA Troy Region meet.
Beavercreek's Taylor Ewert went 17:11.42 for a commanding win in the Division I race.
Region meets will take place at four venues throughout Ohio on Saturday as athletes and teams seek qualification spots to the State Championship.